Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770941 | 0.89 | ADRA1A (0.44) | ADRA1AADRA2AADRB2ADRB1ADRB3 | |
| SCHEMBL8770900 | 0.86 | ADRA1A (0.65) | ADRA1AADRA2AADRB2ADRB1ADRB3 | |
| SCHEMBL8770864 | 0.83 | POLB (0.47) | LMNACYP1A2MTNR1AMTNR1BHTT | |
| SCHEMBL8771128 | 0.82 | ADRA1A (0.60) | ADRA1AADRA2AADRB2ADRB1ADRB3 | |
| SCHEMBL8770954 | 0.81 | ADRA1A (0.67) | ADRA1AADRA2AADRB2ADRB1ADRB3 | |
| SCHEMBL8770891 | 0.78 | MTNR1A (0.50) | LMNACYP1A2TSHRCYP2C19KMT2A | |
| SCHEMBL4392054 | 0.77 | ADRA1A (0.40) | ADRA1AADRA2ALMNACYP1A2TSHR | |
| SCHEMBL8770863 | 0.77 | L3MBTL1 (0.66) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL6704501 | 0.76 | MEN1 (0.41) | ADRA1AADRA2ALMNACYP1A2TSHR | |
| SCHEMBL7025896 | 0.76 | ADRA1A (0.66) | ADRA1AADRA2AADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |