Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508259 | 1.00 | MAOB (0.57) | MAOBNPC1RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL232540 | 0.86 | LMNA (0.59) | MAOBFFAR1ALOX5ALDH1A1NR4A1 | |
| SCHEMBL10317574 | 0.85 | FFAR1 (0.63) | MAOBSMN1; SMN2FFAR1LTA4HALOX5 | |
| SCHEMBL8771189 | 0.85 | FFAR1 (0.63) | MAOBSMN1; SMN2FFAR1LTA4HALOX5 | |
| SCHEMBL8770928 | 0.85 | FFAR1 (0.51) | MAOBFFAR1LTA4HALOX5NR4A1 | |
| SCHEMBL8770884 | 0.85 | KMT2A (0.60) | MAOBSMN1; SMN2ALOX5NR4A2 | |
| SCHEMBL2985256 | 0.85 | MAOB (0.56) | MAOBNPC1RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL17386273 | 0.84 | PRKCA (0.64) | MAOBNPC1RAB9ASMN1; SMN2FFAR1 | |
| Hydrochloric Acid SCHEMBL8324561 | 0.84 | MAOB (0.55) | MAOBNPC1RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL17386272 | 0.84 | PRKCA (0.64) | MAOBNPC1RAB9ASMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |