Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27633524 | 0.84 | L3MBTL1 (0.49) | CTSAL3MBTL1 | |
| SCHEMBL27633523 | 0.84 | L3MBTL1 (0.49) | CTSAL3MBTL1 | |
| SCHEMBL7141329 | 0.84 | FNTA (0.53) | CTSAHTTSMN1; SMN2FNTAFNTB | |
| SCHEMBL8770980 | 0.81 | SLC22A6 (0.37) | CTSAHTTSMN1; SMN2 | |
| SCHEMBL38666095 | 0.81 | SMN1; SMN2 (0.55) | CTSAHTTSMN1; SMN2FNTAFNTB | |
| SCHEMBL825322 | 0.81 | SMN1; SMN2 (0.55) | CTSAHTTSMN1; SMN2FNTAFNTB | |
| SCHEMBL31295271 | 0.81 | SMN1; SMN2 (0.55) | CTSAHTTSMN1; SMN2FNTAFNTB | |
| SCHEMBL21459503 | 0.81 | SMN1; SMN2 (0.55) | CTSAHTTSMN1; SMN2FNTAFNTB | |
| SCHEMBL29478418 | 0.81 | SMN1; SMN2 (0.55) | CTSAHTTSMN1; SMN2FNTAFNTB | |
| SCHEMBL5721007 | 0.81 | SMN1; SMN2 (0.55) | CTSAHTTSMN1; SMN2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |