Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771264 | 0.81 | CTSA (0.51) | CTSASMN1; SMN2HTT | |
| SCHEMBL8770912 | 0.79 | KMT2A (0.42) | — | |
| SCHEMBL19067137 | 0.78 | KMT2A (0.42) | CTSASMN1; SMN2CASP3GABBR2GABBR1 | |
| SCHEMBL8771019 | 0.77 | KCNA5 (0.38) | HTT | |
| Hydrochloric Acid SCHEMBL19949273 | 0.76 | KMT2A (0.41) | CTSASMN1; SMN2CASP3GABBR2GABBR1 | |
| Hydrochloric Acid SCHEMBL19949274 | 0.76 | KMT2A (0.41) | CTSASMN1; SMN2CASP3GABBR2GABBR1 | |
| SCHEMBL29216358 | 0.75 | KDM4E (0.41) | SLC22A6SMN1; SMN2HTT | |
| SCHEMBL8771026 | 0.75 | GABBR2 (0.42) | SLC22A6GABBR2GABBR1 | |
| SCHEMBL7426107 | 0.75 | CES2 (0.47) | SLC22A6CTSASMN1; SMN2 | |
| SCHEMBL8770931 | 0.75 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |