SCHEMBL825322

SCHEMBL825322

NC(CC(=O)O)c1cccc(Br)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.55
KMT2A Q03164 1/20 0.55
CTSA P10619 1/20 0.50
ANPEP P15144 1/20 0.46
ENPEP Q07075 1/20 0.46
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
GABBR2 O75899 1/20 0.43
GABBR1 Q9UBS5 1/20 0.43
SLC6A9 P48067 2/20 0.43
GBA1 P04062 1/20 0.43
HTT P42858 1/20 0.43
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
PARP1 P09874 1/20 0.42
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721007 1.00 SMN1; SMN2 (0.55) SMN1; SMN2KMT2ACTSAANPEPENPEP
SCHEMBL31295274 1.00 SMN1; SMN2 (0.55) SMN1; SMN2KMT2ACTSAANPEPENPEP
SCHEMBL29478418 1.00 SMN1; SMN2 (0.55) SMN1; SMN2KMT2ACTSAANPEPENPEP
SCHEMBL21459503 1.00 SMN1; SMN2 (0.55) SMN1; SMN2KMT2ACTSAANPEPENPEP
SCHEMBL31295271 1.00 SMN1; SMN2 (0.55) SMN1; SMN2KMT2ACTSAANPEPENPEP
SCHEMBL38666095 1.00 SMN1; SMN2 (0.55) SMN1; SMN2KMT2ACTSAANPEPENPEP
Hydrochloric Acid SCHEMBL28252684 0.98 SMN1; SMN2 (0.54) SMN1; SMN2KMT2ACTSAANPEPENPEP
SCHEMBL7141329 0.82 FNTA (0.53) SMN1; SMN2KMT2ACTSAIDO1TDO2
SCHEMBL19067137 0.82 KMT2A (0.42) SMN1; SMN2KMT2ACTSAANPEPENPEP
SCHEMBL8296972 0.81 KCNA5 (0.49) SMN1; SMN2KMT2ACTSAGBA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702157-A1 ACYL-TRNA SYNTHETASES United Kingdom Research and Innovation (GB) 2026-03-04 EP claimed
WO-2024223922-A1 ACYL-tRNA SYNTHETASES UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2024-10-31 WO claimed
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 WO disclosed
EP-3773573-B1 ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) MORPHIC THERAPEUTIC INC (US) 2026-03-18 EP disclosed
EP-4702156-A1 TRNA-BASED METHODS AND RELATED COMPOSITIONS United Kingdom Research and Innovation (GB) 2026-03-04 EP disclosed
EP-4702157-A1 ACYL-TRNA SYNTHETASES United Kingdom Research and Innovation (GB) 2026-03-04 EP disclosed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US disclosed
EP-3700578-B1 SYSTEMS FOR RENAL FUNCTION DETERMINATION MEDIBEACON INC (US) 2025-12-03 EP disclosed
US-20250302971-A1 Therapeutic Nanomaterials UNIV CONNECTICUT (US) 2025-10-02 US disclosed
EP-4622996-A1 CONTROL OF NANOCAGE SELF-ASSEMBLY King's College London (GB) 2025-10-01 EP disclosed
US-20250229081-A1 NANOMATERIAL COATED ELECTRODE AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT 2025-07-17 US disclosed
EP-1621529-A1 3-AMINO-3-ARYLPROPIONIC ACID n-ALKYL ESTERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-3-ARYLPROPIONIC ACIDS AND ESTERS OF THE ANTIPODES THERETO Ube Industries, Ltd. (JP) 2006-02-01 EP disclosed
US-6933294-B2 Thiophene-based tricyclic compounds and pharmaceutical compositions comprising same BRISTOL-MYERS SQUIBB COMPANY (US) 2005-08-23 US disclosed
CN-1582271-A Inhibitors of integrin alpha v beta 6 MERCK PATENT GMBH (DE) 2005-02-16 CN disclosed
EP-1490371-A1 THIOPENE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME Bristol-Myers Squibb Company (US) 2004-12-29 EP disclosed
US-20040092454-A1 Inhibitors of integrin alphavbeta6 MERCK PATENT GMBH (DE) 2004-05-13 US disclosed
US-20040058930-A1 Thiophene-based tricyclic compounds and pharmaceutical compositions comprising same BRISTOL-MYERS SQUIBB COMPANY 2004-03-25 US disclosed
EP-1377540-A1 INHIBITORS OF INTEGRIN AvB6 MERCK PATENT GmbH (DE) 2004-01-07 EP disclosed
WO-2003084959-A1 THIOPENE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME BRISTOL-MYERS SQUIBB COMPANY (US) 2003-10-16 WO disclosed
WO-2002074730-A1 INHIBITORS OF INTEGRIN αvβ¿6? MERCK PATENT GMBH (DE) 2002-09-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302971-A1 Therapeutic Nanomaterials TIE1, TEKT1, POLRMT SMN1; SMN2 2104/4885KMT2A 384/4885CTSA 2973/4885
US-20040058930-A1 Thiophene-based tricyclic compounds and pharmaceutical compositions comprising same ABCG2, PFAS, CYP2F1 SMN1; SMN2 4802/4885KMT2A 4566/4885CTSA 925/4885
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 SMN1; SMN2 1218/4885KMT2A 718/4885CTSA 3353/4885
US-20040092454-A1 Inhibitors of integrin alphavbeta6 ITGB6, ITGB1, ITGA1 SMN1; SMN2 2913/4885KMT2A 3182/4885CTSA 2014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.