Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19266684 | 0.90 | F2 (0.50) | F2ALDH1A1F10GABBR2GABBR1 | |
| SCHEMBL2719599 | 0.85 | F2 (0.61) | F2ALDH1A1F10SMN1; SMN2CYP1A2 | |
| SCHEMBL27323723 | 0.80 | ALDH1A1 (0.55) | F2ALDH1A1F10GABBR2GABBR1 | |
| SCHEMBL2292396 | 0.80 | GABBR2 (0.61) | GABBR2GABBR1CYP1A2CYP2D6LMNA | |
| SCHEMBL28346014 | 0.80 | GABBR2 (0.61) | GABBR2GABBR1CYP1A2CYP2D6LMNA | |
| SCHEMBL9467365 | 0.79 | ALDH1A1 (0.54) | F2ALDH1A1TDP1SMN1; SMN2CHRM2 | |
| SCHEMBL27974827 | 0.79 | F2 (0.46) | F2ALDH1A1F10SMN1; SMN2LMNA | |
| SCHEMBL29012579 | 0.79 | NPC1 (0.52) | F2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9468152 | 0.78 | ALDH1A1 (0.50) | F2ALDH1A1GABBR2GABBR1TDP1 | |
| SCHEMBL8904725 | 0.78 | HDAC3 (0.47) | ALDH1A1GABBR2GABBR1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |