Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988115 | 0.82 | PREP (0.47) | PTGS2MAPTKDM4EALDH1A1ESR1 | |
| SCHEMBL7512743 | 0.82 | PTGS2 (0.46) | PTGS2DRD1PTGS1 | |
| SCHEMBL5597138 | 0.73 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL9672920 | 0.71 | PTGS2 (0.46) | PTGS2KDM4EALDH1A1ESR1ITGB3 | |
| SCHEMBL6176436 | 0.69 | PTGS2 (0.47) | PTGS2KDM4EALDH1A1ESR1ITGB3 | |
| SCHEMBL1452054 | 0.69 | PTGS2 (0.47) | PTGS2POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL1930857 | 0.68 | MAPT (0.74) | PTGS2POLBMAPTPKMKDM4E | |
| SCHEMBL27550707 | 0.67 | PTGS2 (0.45) | PTGS2DRD1PTGS1 | |
| SCHEMBL9671297 | 0.66 | PTGS2 (0.44) | PTGS2KDM4EALDH1A1ESR1ITGB3 | |
| SCHEMBL2698241 | 0.66 | CA1 (0.62) | PTGS2POLBMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788476-A1 | STILBENE DERIVATIVES USEFUL AS CYCLOOXYGENASE-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-08-13 | — | — | EP | claimed |
| WO-1996013483-A1 | STILBENE DERIVATIVES USEFUL AS CYCLOOXYGENASE-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1996-05-09 | — | — | WO | claimed |