Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497815 | 0.83 | CA12 (0.48) | PTGS2KIF11PTGS1 | |
| SCHEMBL7512743 | 0.78 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL150096 | 0.76 | MAOB (0.32) | — | |
| SCHEMBL3607306 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL6044343 | 0.73 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL27550733 | 0.73 | PTGS2 (0.42) | PTGS2 | |
| SCHEMBL435279 | 0.73 | CYP1A2 (0.38) | — | |
| SCHEMBL1491042 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL8771737 | 0.73 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL8074244 | 0.72 | FAAH (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039914-A4 | CYCLOOXYGENASE-2 INHIBITION | CORNELL RES FOUNDATION INC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1039914-A1 | CYCLOOXYGENASE-2 INHIBITION | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999030721-A1 | CYCLOOXYGENASE-2 INHIBITION | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-06-24 | — | — | WO | disclosed |