Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 7/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818247 | 0.92 | TDP1 (0.41) | PIN1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23580618 | 0.78 | TDP1 (0.41) | PIN1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3590495 | 0.78 | TDP1 (0.41) | PIN1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31093759 | 0.75 | CYP1A2 (0.41) | PIN1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28488316 | 0.74 | TDP1 (0.41) | PIN1TDP1MEN1KMT2ASMN1; SMN2 | |
| Formamide SCHEMBL8771580 | 0.74 | UHRF1 (0.32) | KMT2A | |
| Formamide SCHEMBL29002500 | 0.73 | ALDH1A1 (0.36) | PIN1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8393167 | 0.72 | SMN1; SMN2 (0.42) | PIN1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9149365 | 0.72 | TDP1 (0.42) | PIN1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17364540 | 0.72 | TDP1 (0.42) | TDP1MEN1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473267-B1 | Acylaminopyridinecarboxamides, process for their preparation and their use as fungicides | ZENECA LTD (GB) | 1997-10-01 | — | — | EP | disclosed |
| EP-0473267-A2 | Acylaminopyridinecarboxamides, process for their preparation and their use as fungicides | ZENECA LIMITED (GB) | 1992-03-04 | — | — | EP | disclosed |