Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 7/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818247 | 0.85 | TDP1 (0.41) | TDP1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL25334109 | 0.81 | CYP1A2 (0.41) | TDP1MEN1KMT2ASMN1; SMN2PIN1 | |
| SCHEMBL18855622 | 0.81 | PIN1 (0.40) | TDP1SMN1; SMN2TSHRPIN1CRHBP | |
| Formamide SCHEMBL8771746 | 0.78 | PIN1 (0.35) | TDP1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL23580618 | 0.77 | TDP1 (0.41) | TDP1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL3581470 | 0.77 | GPR35 (0.47) | TDP1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL25337904 | 0.75 | PIN1 (0.48) | TDP1SMN1; SMN2PIN1ALDH1A1MAPT | |
| SCHEMBL9149365 | 0.74 | TDP1 (0.42) | TDP1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL29863305 | 0.74 | GPR35 (0.50) | TDP1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL17364540 | 0.74 | TDP1 (0.42) | TDP1MEN1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784403-B1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2013-07-17 | — | — | EP | disclosed |
| CN-101010321-B | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORP | 2011-10-26 | — | — | CN | disclosed |
| US-7642269-B2 | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2010-01-05 | — | — | US | disclosed |
| US-20070213358-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2007-09-13 | — | — | US | disclosed |
| CN-101010321-A | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORP (KR) | 2007-08-01 | — | — | CN | disclosed |
| EP-1784403-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006038773-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213358-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, PPOX | TDP1 3248/4885MEN1 2718/4885KMT2A 3542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.