SCHEMBL8771785

SCHEMBL8771785

CCC[C@@H](C(N)=O)N(C(=O)Oc1ccccc1)C(C)COc1ccc(C#N)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.43
GPR88 Q9GZN0 2/20 0.40
MMP3 P08254 2/20 0.39
MGLL Q99685 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
CYP11B1 P15538 2/20 0.38
CYP11B2 P19099 2/20 0.38
MAOB P27338 1/20 0.37
ALOX5 P09917 1/20 0.36
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
ABCB11 O95342 1/20 0.35
KCNH2 Q12809 1/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771940 0.89 MMP2 (0.43) MMP2GPR88MMP3ALDH1A1HPGD
SCHEMBL8771901 0.85 MMP2 (0.45) MMP2MMP3ALDH1A1HPGDCYP11B1
SCHEMBL8771861 0.77 MMP2 (0.43) MMP2MMP3ALDH1A1HPGDCYP11B1
SCHEMBL8771767 0.76 MMP2 (0.44) MMP2MMP3ALDH1A1HPGDMAOB
SCHEMBL8771846 0.74 MMP2 (0.41) MMP2MMP3ALDH1A1HPGDCYP11B1
SCHEMBL8771794 0.72 MMP2 (0.43) MMP2MMP3ALDH1A1HPGDMAOB
SCHEMBL8771958 0.71 MMP2 (0.42) MMP2MMP3ALDH1A1HPGDCYP11B1
SCHEMBL8771750 0.69 EPHX1 (0.44) GPR88ALDH1A1MAOBALOX5FFAR1
SCHEMBL8771829 0.69 PSMB5 (0.40) ALDH1A1MAOB
SCHEMBL8771789 0.69 MTNR1A (0.47) MMP2GPR88MMP3MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648740-B1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-10-08 EP disclosed