SCHEMBL8771829

SCHEMBL8771829

CC(C)[C@@H](C(N)=O)N(C(=O)Oc1ccccc1)C(C)COc1ccc(C(F)(F)F)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.40
LIPE Q05469 3/20 0.40
KIF11 P52732 1/20 0.39
PPARD Q03181 5/20 0.39
SCN1A P35498 2/20 0.38
SCN5A Q14524 2/20 0.38
SCN9A Q15858 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MAOB P27338 1/20 0.37
ALDH1A1 P00352 1/20 0.37
BACE1 P56817 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
ADAMTS4 O75173 1/20 0.37
MMP13 P45452 1/20 0.37
SLC6A9 P48067 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771750 0.90 EPHX1 (0.44) KIF11MAOBALDH1A1
SCHEMBL8771901 0.84 MMP2 (0.45) MAOBALDH1A1BACE1ADAMTS4MMP13
SCHEMBL8771767 0.77 MMP2 (0.44) SCN9AMAOBALDH1A1
SCHEMBL8772026 0.77 MTNR1A (0.40) MEN1KMT2AMAOBALDH1A1
SCHEMBL8771818 0.76 LIPE (0.47) LIPESCN9APPARGPPARA
SCHEMBL8771861 0.74 MMP2 (0.43) MAOBALDH1A1ADAMTS4MMP13
SCHEMBL8771846 0.74 MMP2 (0.41) MAOBALDH1A1
SCHEMBL8771937 0.72 TDP1 (0.38) SCN9AMEN1KMT2AALDH1A1
SCHEMBL8771794 0.71 MMP2 (0.43) SCN9AMEN1KMT2AMAOBALDH1A1
SCHEMBL8771940 0.70 MMP2 (0.43) MAOBALDH1A1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648740-B1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-10-08 EP disclosed