Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 8/20 | 0.48 |
| ▸ | RXRB | P28702 | 8/20 | 0.48 |
| ▸ | RXRG | P48443 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771810 | 0.90 | KMT2A (0.48) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17275573 | 0.80 | RARB (0.50) | RXRASRD5A2POLB | |
| SCHEMBL4653407 | 0.76 | RARB (0.69) | RXRASRD5A2 | |
| SCHEMBL4653408 | 0.76 | RARB (0.69) | RXRASRD5A2 | |
| SCHEMBL4653505 | 0.74 | RXRA (0.53) | RXRARXRBSRD5A2 | |
| SCHEMBL4653413 | 0.74 | RARA (0.71) | RXRAP2RY14TSHR | |
| SCHEMBL8674842 | 0.73 | RXRA (0.68) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL1756343 | 0.73 | NR4A2 (0.81) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL5582767 | 0.73 | NR4A2 (0.81) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8437505 | 0.72 | NR4A2 (0.62) | NR4A2NR4A1NR4A3RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661259-B1 | Substituted (5,6)-dihydronaphthalenyl compounds having retinoid-like activity | BRISTOL MYERS SQUIBB CO (US) | 1997-10-08 | — | — | EP | claimed |
| US-5618839-A | Retinoid-like compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-04-08 | — | — | US | disclosed |