Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 12/20 | 0.61 |
| ▸ | RARB | P10826 | 11/20 | 0.61 |
| ▸ | RARG | P13631 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | BLVRB | P30043 | 1/20 | 0.54 |
| ▸ | FABP1 | P07148 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653413 | 0.93 | RARA (0.71) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL8771705 | 0.90 | PTPN1 (0.55) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL17275573 | 0.83 | RARB (0.50) | RARARARBRARGKMT2AALDH1A1 | |
| SCHEMBL4652336 | 0.83 | RARA (0.88) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL8771636 | 0.83 | RARA (0.58) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL4653408 | 0.79 | RARB (0.69) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL4653407 | 0.79 | RARB (0.69) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL4653505 | 0.77 | RXRA (0.53) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8771689 | 0.76 | PDK2 (0.49) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL4757231 | 0.76 | RARA (1.00) | RARARARBRARGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661259-B1 | Substituted (5,6)-dihydronaphthalenyl compounds having retinoid-like activity | BRISTOL MYERS SQUIBB CO (US) | 1997-10-08 | — | — | EP | claimed |
| US-5618839-A | Retinoid-like compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-04-08 | — | — | US | claimed |
| CN-1144217-A | Retinoid-like compounds | BRISTOL MYERS SQUIBB CO (US) | 1997-03-05 | — | — | CN | claimed |
| EP-0661259-A1 | Substituted (5,6)-dihydronaphthalenyl compounds having retinoid-like activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-05 | — | — | EP | claimed |
| US-5618839-A | Retinoid-like compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-04-08 | — | — | US | disclosed |