Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031544 | 0.78 | — | — | |
| SCHEMBL28199070 | 0.76 | PYGL (0.41) | ALDH1A1KDM4E | |
| SCHEMBL27552331 | 0.76 | PYGL (0.41) | ALDH1A1KDM4E | |
| SCHEMBL27948335 | 0.76 | PYGL (0.41) | ALDH1A1KDM4E | |
| SCHEMBL2983115 | 0.76 | PDPK1 (0.45) | CDK2CDK1CCNB1 | |
| Water SCHEMBL27761338 | 0.75 | PDPK1 (0.44) | CDK2CDK1CCNB1 | |
| SCHEMBL1378385 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4EPAK1CDK2RXFP1 | |
| SCHEMBL2117131 | 0.73 | PDPK1 (0.45) | CDK2CDK1CCNB1 | |
| 2-Aminopurine SCHEMBL1507729 | 0.72 | ALDH1A1 (0.55) | ALDH1A1KDM4EPAK1CDK2RXFP1 | |
| SCHEMBL9854792 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EPAK1CDK2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788507-A1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INTERNATIONAL, INC. (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996012728-A1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INTERNATIONAL, INC. (US) | 1996-05-02 | — | — | WO | disclosed |