Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Aminopurine SCHEMBL28775710 | 0.81 | ALDH1A1 (0.59) | ALDH1A1RXFP1KDM4EPAK1DNMT1 | |
| 2-Aminopurine SCHEMBL1919609 | 0.81 | ALDH1A1 (0.55) | ALDH1A1RXFP1KDM4EPAK1DNMT1 | |
| 2,6-Diaminopurine SCHEMBL443468 | 0.81 | PDPK1 (0.55) | CDK2CDK1CCNB1PDPK1GDA | |
| Purine SCHEMBL4378871 | 0.81 | TREH (0.33) | — | |
| SCHEMBL15602792 | 0.79 | PDPK1 (0.40) | CDK2CDK1CCNB1PDPK1GDA | |
| Adenine SCHEMBL593934 | 0.75 | PI4KA (0.54) | LMNAHTTCDK2CDK1PDPK1 | |
| 2-Aminopurine SCHEMBL4342854 | 0.74 | ALDH1A1 (0.79) | ALDH1A1RXFP1KDM4EPAK1CDK2 | |
| 2-Aminopurine SCHEMBL5634 | 0.74 | ALDH1A1 (1.00) | ALDH1A1RXFP1KDM4EPAK1LMNA | |
| Guanine SCHEMBL4198112 | 0.74 | PNP (0.58) | ALDH1A1KDM4EGDA | |
| 2-Aminopurine SCHEMBL357699 | 0.72 | ALDH1A1 (0.96) | ALDH1A1RXFP1KDM4EPAK1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352846-B1 | RNA DETECTION METHOD | RIBOXX GMBH (DE) | 2015-01-07 | — | — | EP | disclosed |
| EP-2463385-B1 | Kit for RNA detection | RIBOXX GMBH (DE) | 2014-08-27 | — | — | EP | disclosed |
| EP-2673376-A1 | METHOD FOR THE DETECTION OF POLYNUCLEOTIDE SEQUENCES | RiboxX GmbH (DE) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107537-A1 | METHOD FOR THE DETECTION OF POLYNUCLEOTIDE SEQUENCES | RIBOXX GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| EP-2463385-A1 | Kit for RNA detection | RiboxX GmbH (DE) | 2012-06-13 | — | — | EP | disclosed |
| US-20110212451-A1 | RNA DETECTION METHOD | RIBOXX GMBH (DE) | 2011-09-01 | — | — | US | disclosed |
| EP-2352846-A1 | RNA DETECTION METHOD | Riboxx GmbH (DE) | 2011-08-10 | — | — | EP | disclosed |
| EP-2298935-A1 | Methods for detection of a target nucleic acid sequence | Hologic Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| US-7846661-B2 | Methods of detecting an amplified nucleic acid | HOLOGIC, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-7838225-B2 | Methods for detection of a target nucleic acid by forming a cleavage structure using a reverse transcriptase | HOLOGIC, INC. (US) | 2010-11-23 | — | — | US | disclosed |
| US-6350580-B1 | GENERATING A SIGNAL INDICATIVE OF A TARGET NUCLEIC ACID IN A SAMPLE BY INCUBATING THE NUCLEIC ACID WITH A PROBE THAT CHANGES ITS SECONDARY STRUCTURE UPON BINDING OF A PROBE TO THE TARGET AND CLEAVING A CLEAVAGE STRUCTURE WITH A NUCLEASE | STRATAGENE | 2002-02-26 | — | — | US | disclosed |
| WO-2001044220-A2 | FLUORESCENT NUCLEOSIDE ANALOGS AND COMBINATORIAL FLUOROPHORE ARRAYS COMPRISING SAME | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001032922-A2 | METHODS FOR DETECTION OF A TARGET NUCLEIC ACID SEQUENCE | STRATAGENE (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6214979-B1 | Homogeneous assay system | ROCHE MOLECULAR SYSTEMS | 2001-04-10 | — | — | US | disclosed |
| EP-0543942-B1 | HOMOGENEOUS ASSAY SYSTEM | HOFFMANN LA ROCHE (CH) | 2001-01-24 | — | — | EP | disclosed |
| EP-0919565-A2 | Labeled oligonucleotides | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-02 | — | — | EP | disclosed |
| US-5804375-A | PAIR OF NUCLEOTIDE PRIMERS AND LABELED OLIGONUCLEOTIDE | ROCHE MOLECULAR SYSTEMS, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| US-5487972-A | POLYMERASE CHAIN REACTION AMPLIFICATION | HOFFMANN-LA ROCHE INC. (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0543942-A1 | HOMOGENEOUS ASSAY SYSTEM | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992002638-A1 | HOMOGENEOUS ASSAY SYSTEM | F. HOFFMANN-LA ROCHE AG (CH) | 1992-02-20 | — | — | WO | disclosed |