SCHEMBL8771946

SCHEMBL8771946

CC(CN(C)c1ccc(F)cc1)NC(=O)[C@@H](NC(=O)Oc1ccccc1)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.40
ALDH1A1 P00352 4/20 0.39
MAPT P10636 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 2/20 0.39
THRB P10828 1/20 0.39
GFER P55789 1/20 0.39
BCHE P06276 4/20 0.39
ACHE P22303 4/20 0.39
CYP1A2 P05177 3/20 0.38
CYP3A4 P08684 3/20 0.38
CYP2C9 P11712 3/20 0.38
CYP2C19 P33261 3/20 0.38
TSHR P16473 2/20 0.38
CYP2D6 P10635 2/20 0.38
CCR1 P32246 1/20 0.38
ELANE P08246 1/20 0.36
FAAH O00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771995 0.91 MEN1 (0.40) SLC1A3ALDH1A1MAPTTDP1MEN1
SCHEMBL9229856 0.84 ALDH1A1 (0.39) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL9223979 0.78 MEN1 (0.37) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL8772029 0.73 MTNR1A (0.56) SLC1A3ALDH1A1KDM4ECYP1A2TSHR
SCHEMBL8681853 0.72 MAPK1 (0.54) SLC1A3ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL8605495 0.72 MAPK1 (0.54) SLC1A3ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL8606112 0.71 SLC1A3 (0.51) SLC1A3ALDH1A1MAPTMEN1KMT2A
SCHEMBL8606117 0.71 SLC1A3 (0.51) SLC1A3ALDH1A1MAPTMEN1KMT2A
SCHEMBL3363885 0.70 SLC1A3 (0.69) SLC1A3ALDH1A1MAPTMEN1KMT2A
SCHEMBL1953003 0.70 SLC1A3 (0.69) SLC1A3ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648740-B1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-10-08 EP disclosed
EP-0648740-A1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1995-04-19 EP disclosed