SCHEMBL8771995

SCHEMBL8771995

CC[C@H](C)[C@H](NC(=O)Oc1ccccc1)C(=O)NC(C)CN(C)c1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CTSL P07711 2/20 0.39
CTSB P07858 2/20 0.39
CTSS P25774 2/20 0.39
CYP1A2 P05177 3/20 0.39
FAAH O00519 2/20 0.39
LMNA P02545 1/20 0.38
SLC1A3 P43003 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 1/20 0.37
THRB P10828 1/20 0.37
GFER P55789 1/20 0.37
CTSK P43235 1/20 0.37
CYP2C9 P11712 3/20 0.37
CYP2C19 P33261 3/20 0.37
POLB P06746 1/20 0.37
BCHE P06276 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771946 0.91 SLC1A3 (0.40) MEN1KMT2ACYP1A2FAAHSLC1A3
SCHEMBL9223979 0.85 MEN1 (0.37) MEN1KMT2ACTSLCTSBCTSS
SCHEMBL9229856 0.78 ALDH1A1 (0.39) MEN1KMT2ACYP1A2FAAHLMNA
SCHEMBL8607221 0.74 SLC1A3 (0.61) MEN1KMT2ACTSLCTSBCTSS
SCHEMBL5256446 0.74 SLC1A3 (0.61) MEN1KMT2ACTSLCTSBCTSS
SCHEMBL5256444 0.74 SLC1A3 (0.61) MEN1KMT2ACTSLCTSBCTSS
SCHEMBL28232199 0.72 CYP1A2 (0.54) CTSLCTSBCTSSCYP1A2FAAH
SCHEMBL8771990 0.70 GPR88 (0.38) ALDH1A1TDP1
SCHEMBL11060563 0.68 CYP1A2 (0.58) MEN1KMT2ACYP1A2FAAHLMNA
SCHEMBL27764271 0.67 ALDH1A1 (0.61) CYP1A2FAAHLMNASLC1A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648740-B1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-10-08 EP disclosed
EP-0648740-A1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1995-04-19 EP disclosed