Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.35 |
| ▸ | TK1 | P04183 | 3/20 | 0.34 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.33 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919491 | 0.87 | TYMP (0.37) | TK1NT5MTYMPHPGDTK2 | |
| SCHEMBL5188453 | 0.82 | TOP2A (0.41) | TOP2ATK1NT5MTK2RNASE1 | |
| SCHEMBL5188458 | 0.82 | TOP2A (0.41) | TOP2ATK1NT5MTK2RNASE1 | |
| SCHEMBL12942597 | 0.82 | TOP2A (0.41) | TOP2ATK1NT5MTK2RNASE1 | |
| SCHEMBL8069871 | 0.80 | TYMP (0.37) | TK1NT5MTYMPHPGDTK2 | |
| SCHEMBL15086978 | 0.76 | TK1 (0.38) | TOP2ATK1NT5MTYMPTK2 | |
| SCHEMBL11985217 | 0.76 | TK1 (0.38) | TOP2ATK1NT5MTYMPTK2 | |
| SCHEMBL18652716 | 0.76 | TK1 (0.38) | TOP2ATK1NT5MTYMPTK2 | |
| SCHEMBL15087050 | 0.76 | TK1 (0.38) | TOP2ATK1NT5MTYMPTK2 | |
| SCHEMBL25399881 | 0.76 | TSHR (0.36) | TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799834-A1 | Modified nucleotides | Novartis AG (CH) | 1997-10-08 | — | — | EP | disclosed |