Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919491 | 0.90 | TYMP (0.37) | TYMPTK1ALDH1A1LMNAALB | |
| SCHEMBL8772083 | 0.80 | TOP2A (0.35) | TYMPTK1RNASE1TK2HPGD | |
| SCHEMBL10644833 | 0.76 | TOP2A (0.41) | TYMPTK1RNASE1TK2 | |
| SCHEMBL10647357 | 0.76 | TK2 (0.45) | TYMPTK1ALDH1A1RNASE1TK2 | |
| SCHEMBL10646821 | 0.76 | TOP2A (0.41) | TYMPTK1RNASE1TK2 | |
| SCHEMBL10643570 | 0.76 | TK2 (0.45) | TYMPTK1ALDH1A1RNASE1TK2 | |
| SCHEMBL13615609 | 0.75 | TK1 (0.36) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL12180655 | 0.74 | TK1 (0.38) | TYMPTK1ALDH1A1LMNAALB | |
| SCHEMBL14828583 | 0.74 | TK1 (0.38) | TYMPTK1ALDH1A1LMNAALB | |
| SCHEMBL12180657 | 0.74 | TYMP (0.44) | TYMPTK1ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025482-A | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling | ISIS PHARMACEUTICALS, INC. (US) | 2000-02-15 | — | — | US | disclosed |