SCHEMBL8772267

SCHEMBL8772267

Cc1cc(Cc2cc(C)c(O)c3ccccc23)cc(C)c1O

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
HTT P42858 1/20 0.53
PKM P14618 1/20 0.50
SHBG P04278 1/20 0.50
ALK Q9UM73 1/20 0.47
HMGB1 P09429 1/20 0.45
CXCL12 P48061 1/20 0.45
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772263 0.89 LMNA (0.53) LMNAHTTPKM
SCHEMBL1151311 0.89 HTT (0.61) LMNAHTTPKMSHBGHMGB1
SCHEMBL8772341 0.87 LMNA (0.47) LMNAHTTPKMSHBGALK
SCHEMBL8963163 0.87 LMNA (0.47) LMNAHTTPKMSHBGALK
SCHEMBL8772326 0.87 ESR1 (0.58) LMNAHTTPKMSHBGHMGB1
SCHEMBL8772359 0.86 LMNA (0.50) LMNAHTTPKMALKHMGB1
SCHEMBL8772373 0.86 LMNA (0.50) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8772324 0.86 CYP2C9 (0.44) LMNAHTTPKMSHBGALK
SCHEMBL8772299 0.84 LMNA (0.45) LMNAHTTPKMSHBGALDH1A1
SCHEMBL8772258 0.84 KDM4E (0.46) LMNAHTTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
US-5543286-A CONTAINING AN ORGANIC SILVER SALT AND A PYRROLE COMPOUND;HIGH CONTRAST IMAGES CANON KABUSHIKI KAISHA (JP) 1996-08-06 US disclosed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
US-5258281-A Light sensitive silver halide multilayer elements with dyes and heat development accelerators CANON KABUSHIKI KAISHA (JP) 1993-11-02 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0509740-A1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed
EP-0505155-A1 Heat-developable masking layer CANON KABUSHIKI KAISHA (JP) 1992-09-23 EP disclosed
EP-0486246-A1 Heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-05-20 EP disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
EP-0453317-A2 Image forming medium CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed