SCHEMBL8772373

SCHEMBL8772373

Cc1cc(Cc2ccc(O)cc2)c2ccccc2c1O

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
KEAP1 Q14145 1/20 0.49
PKM P14618 1/20 0.47
HMGB1 P09429 1/20 0.42
CXCL12 P48061 1/20 0.42
ALOX5 P09917 1/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772359 0.90 LMNA (0.50) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8772263 0.90 LMNA (0.53) LMNAHTTPKM
SCHEMBL8772267 0.86 LMNA (0.53) LMNAHTTPKMHMGB1CXCL12
SCHEMBL1151311 0.86 HTT (0.61) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8772294 0.84 G6PD (0.50) LMNAHTTPKMHMGB1CXCL12
SCHEMBL19039045 0.84 KEAP1 (0.53) KEAP1ESR1ESR2
SCHEMBL8772326 0.84 ESR1 (0.58) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8962592 0.82 KEAP1 (0.47) KEAP1HMGB1CXCL12
SCHEMBL8772341 0.81 LMNA (0.47) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8963163 0.81 LMNA (0.47) LMNAHTTPKMHMGB1CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed