SCHEMBL8772326

SCHEMBL8772326

Cc1cc(Cc2cc(C)c(O)c3ccccc23)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.51
PKM P14618 1/20 0.45
SHBG P04278 1/20 0.41
HMGB1 P09429 1/20 0.41
CXCL12 P48061 1/20 0.41
NQO1 P15559 1/20 0.40
IDH1 O75874 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772267 0.87 LMNA (0.53) LMNAHTTPKMSHBGHMGB1
SCHEMBL8772315 0.87 CYP3A4 (0.52) ESR1ESR2LMNAHTTPKM
SCHEMBL8772307 0.84 BACE1 (0.48) ESR1ESR2LMNAHTTPKM
SCHEMBL8772373 0.84 LMNA (0.50) ESR1ESR2LMNAHTTPKM
SCHEMBL8772359 0.84 LMNA (0.50) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8772263 0.83 LMNA (0.53) LMNAHTTPKM
SCHEMBL1151311 0.83 HTT (0.61) LMNAHTTPKMSHBGHMGB1
SCHEMBL8772261 0.79 NUDT1 (0.49) ESR1ESR2LMNAHTTPKM
SCHEMBL8772294 0.79 G6PD (0.50) LMNAHTTPKMHMGB1CXCL12
SCHEMBL9172537 0.79 HTT (0.56) LMNAHTTPKMHMGB1CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed