SCHEMBL8772328

SCHEMBL8772328

CC(C)(C)c1cc(Cc2ccc(Cl)cc2)cc(C2CCCCC2)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.39
BACE1 P56817 1/20 0.39
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
PTGDR2 Q9Y5Y4 8/20 0.36
PTGDR Q13258 5/20 0.36
GAA P10253 2/20 0.36
PTGER2 P43116 1/20 0.36
HSPA5 P11021 1/20 0.35
POLB P06746 1/20 0.35
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
LTA4H P09960 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772283 0.89 ALDH1A1 (0.45) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9816995 0.82 NUDT1 (0.53) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9182008 0.79 ALDH1A1 (0.43) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9184712 0.78 ALDH1A1 (0.42) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9182462 0.78 ALDH1A1 (0.42) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9176725 0.78 ALDH1A1 (0.42) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL6567025 0.78 ALDH1A1 (0.42) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9181332 0.78 ALDH1A1 (0.42) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9176613 0.78 ALDH1A1 (0.42) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9184731 0.78 ALDH1A1 (0.42) NUDT1BACE1ALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed