SCHEMBL9816995

SCHEMBL9816995

CC(C)(C)c1cc(Cc2ccc(O)c(C3CCCCC3)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.53
BACE1 P56817 1/20 0.53
ALDH1A1 P00352 8/20 0.43
KDM4E B2RXH2 4/20 0.43
TDP1 Q9NUW8 1/20 0.43
HSP90AA1 P07900 1/20 0.41
GAA P10253 3/20 0.40
MAPT P10636 4/20 0.40
TSHR P16473 3/20 0.38
LMNA P02545 2/20 0.38
CYP1A2 P05177 3/20 0.37
ATM Q13315 3/20 0.37
CYP2C19 P33261 2/20 0.37
ALOX15 P16050 2/20 0.37
MEN1 O00255 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 2/20 0.37
BLM P54132 2/20 0.37
KMT2A Q03164 2/20 0.37
HIF1A Q16665 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772283 0.86 ALDH1A1 (0.45) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL7182409 0.84 NUDT1 (0.71) NUDT1BACE1KDM4EHSP90AA1GAA
SCHEMBL8772328 0.82 NUDT1 (0.39) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL28171805 0.79 ESR1 (0.61) NUDT1BACE1TDP1HSP90AA1GAA
SCHEMBL27936312 0.79 NUDT1 (0.63) NUDT1BACE1HSP90AA1CYP3A4CYP2C9
Butylated Hydroxytoluene SCHEMBL28933654 0.78 ALDH1A1 (0.50) NUDT1BACE1ALDH1A1KDM4ETDP1
SCHEMBL9817034 0.78 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1GAAMAPT
SCHEMBL30375450 0.78 NUDT1 (0.52) NUDT1BACE1HSP90AA1MAPTCYP1A2
SCHEMBL29636450 0.78 NUDT1 (0.52) NUDT1BACE1HSP90AA1MAPTCYP1A2
SCHEMBL4056228 0.78 NUDT1 (0.52) NUDT1BACE1HSP90AA1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0453317-A2 Image forming medium CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed