SCHEMBL8772338

SCHEMBL8772338

CC(C)(C)c1cc(Cc2cccc3ccccc23)cc(C(C)(C)C)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.48
CETP P11597 1/20 0.45
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSPA5 P11021 1/20 0.44
AKR1B1 P15121 1/20 0.44
CA2 P00918 1/20 0.43
LMNA P02545 2/20 0.43
NR1I2 O75469 1/20 0.43
ADRA2A P08913 1/20 0.43
CYP2D6 P10635 1/20 0.43
ACHE P22303 1/20 0.43
SLC6A2 P23975 1/20 0.43
HTR2A P28223 1/20 0.43
SLC6A4 P31645 1/20 0.43
KCNH2 Q12809 1/20 0.43
SIGMAR1 Q99720 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9833121 0.92 CYP2C19 (0.47) DHFRCETPCYP3A4CYP2C19AKR1B1
SCHEMBL28384212 0.85 HSPA5 (0.53) DHFRGAAMEN1KMT2ACYP3A4
SCHEMBL30464059 0.85 HSPA5 (0.53) DHFRGAAMEN1KMT2ACYP3A4
SCHEMBL292109 0.81 HSPA5 (0.50) DHFRGAAMEN1KMT2ACYP3A4
SCHEMBL2042110 0.81 DHFR (0.49) DHFRGAAMEN1KMT2ACYP3A4
SCHEMBL8772273 0.81 MEN1 (0.49) DHFRGAAMEN1KMT2ACYP3A4
SCHEMBL9817051 0.81 CA2 (0.59) DHFRGAAMEN1KMT2ACYP3A4
SCHEMBL8772220 0.80 CYP3A4 (0.55) CETPCYP3A4CYP2C19CYP2D6ALDH1A1
SCHEMBL11338062 0.79 MEN1 (0.50) DHFRGAAMEN1KMT2ACYP3A4
SCHEMBL2517595 0.78 PARP10 (0.50) MEN1KMT2ACYP3A4CYP2C19AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed