SCHEMBL8772220

SCHEMBL8772220

Cc1cc(Cc2cccc3ccccc23)cc(C)c1O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.55
CYP2C19 P33261 3/20 0.55
NQO1 P15559 1/20 0.51
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
P2RX3 P56373 1/20 0.48
CETP P11597 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
SHBG P04278 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP2A6 P11509 1/20 0.47
IDH1 O75874 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9833121 0.87 CYP2C19 (0.47) CYP3A4CYP2C19NQO1P2RX3CETP
SCHEMBL13609064 0.82 ALDH1A1 (0.52) PTGS1PTGS2SHBGALDH1A1
SCHEMBL11810411 0.81 CYP3A4 (0.56) CYP3A4CYP2C19NQO1PTGS1PTGS2
SCHEMBL5406194 0.80 ALDH1A1 (0.56) PTGS1PTGS2SHBGALDH1A1
SCHEMBL8990145 0.80 LMNA (0.50) SHBG
SCHEMBL8772338 0.80 DHFR (0.48) CYP3A4CYP2C19NQO1CETPCYP2D6
SCHEMBL8772267 0.79 LMNA (0.53) SHBGALDH1A1
SCHEMBL4065746 0.79 HSPA5 (0.56) SHBGALDH1A1IDH1
SCHEMBL25382071 0.78 CYP2C19 (0.65) CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
SCHEMBL26794965 0.78 POLB (0.45) CYP3A4CYP2C19NQO1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed