SCHEMBL8772352

SCHEMBL8772352

Cc1cc(Cc2cc(C)c(O)c(C3CCCCC3)c2)cc(C2CCCCC2)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.44
NUDT1 P36639 1/20 0.43
BACE1 P56817 1/20 0.43
HMGB1 P09429 1/20 0.42
CXCL12 P48061 1/20 0.42
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2D6 P10635 3/20 0.36
CYP2C9 P11712 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
PSMB5 P28074 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.35
ACHE P22303 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27584474 0.91 NUDT1 (0.43) SHBGNUDT1BACE1HMGB1CXCL12
SCHEMBL10434190 0.90 SHBG (0.44) SHBGNUDT1BACE1HMGB1CXCL12
SCHEMBL21409960 0.89 SHBG (0.46) SHBGNUDT1BACE1HMGB1CXCL12
SCHEMBL27584476 0.87 OPRM1 (0.41) NUDT1BACE1ESR1ESR2
SCHEMBL11614576 0.87 NUDT1 (0.49) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL27861753 0.87 NUDT1 (0.48) SHBGNUDT1BACE1KDM4EMEN1
SCHEMBL9182898 0.87 NUDT1 (0.44) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9182097 0.85 NUDT1 (0.43) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9184001 0.85 NUDT1 (0.43) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9178157 0.85 NUDT1 (0.43) NUDT1BACE1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed