SCHEMBL8778047

SCHEMBL8778047

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C2c1ccc(N(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 7/20 0.46
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
GAA P10253 4/20 0.46
HTT P42858 4/20 0.46
TSHR P16473 4/20 0.46
CYP3A4 P08684 4/20 0.46
CASP1 P29466 3/20 0.46
CASP7 P55210 3/20 0.46
USP2 O75604 2/20 0.46
NPC1 O15118 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
BRCA1 P38398 1/20 0.46
HBB P68871 1/20 0.46
MAPT P10636 5/20 0.42
LMNA P02545 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11520111 0.92 MEN1 (0.48) NPSR1MEN1KMT2AGAAHTT
SCHEMBL11289610 0.88 MEN1 (0.46) NPSR1MEN1KMT2AGAAHTT
SCHEMBL8778242 0.88 ALOX15 (0.47) NPSR1MEN1KMT2AGAAHTT
SCHEMBL82135 0.87 MEN1 (0.52) NPSR1MEN1KMT2AGAAHTT
SCHEMBL9803564 0.83 S100B (0.41) NPSR1MEN1KMT2AGAAHTT
Nitric Acid SCHEMBL27979944 0.82 MEN1 (0.44) NPSR1MEN1KMT2AGAAHTT
SCHEMBL18213659 0.82 KMT2A (0.42) NPSR1MEN1KMT2AGAAHTT
SCHEMBL391014 0.82 MAPT (0.44) NPSR1MEN1KMT2AGAAHTT
SCHEMBL10020930 0.82 MAPT (0.44) NPSR1MEN1KMT2AGAAHTT
SCHEMBL390797 0.81 ALDH1A1 (0.40) NPSR1MEN1KMT2AGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US claimed
EP-0576622-B1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK CO (US) 1997-11-05 EP disclosed
EP-0643333-A1 Donor element for use in a dry color proofing process EASTMAN KODAK COMPANY (US) 1995-03-15 EP disclosed
US-5374497-A Support, photosensitive imaging layer, print-out layer; multicolor EASTMAN KODAK COMPANY (US) 1994-12-20 US disclosed
EP-0576622-A1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
WO-1992017821-A1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1992-10-15 WO disclosed
US-5141839-A LITHOGRAPHIC PRINTING PLATES HAVING A RADIATION-SENSITIVE LAYER COMPRISING A PHOTOCROSSLINKABLE POLYMER, A LEUCO DYE, A PHOTOOXIDANT AND A HETEROAROMATIC AMINE N-OXIDE EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed
US-5141842-A Negative working lithography printing plates EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed
US-4425424-A LEUCO DYE AND N-SULFONYLOXY PHOTOOXIDANT EASTMAN KODAK COMPANY (US) 1984-01-10 US disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed