SCHEMBL8772396

SCHEMBL8772396

Oc1ccc(O)c(C(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.52
GAA P10253 3/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALOX5 P09917 3/20 0.42
NQO1 P15559 1/20 0.41
POLB P06746 1/20 0.39
GFER P55789 1/20 0.39
LMNA P02545 2/20 0.38
NFE2L2 Q16236 2/20 0.38
NR1I2 O75469 1/20 0.38
CYP2C9 P11712 1/20 0.38
MIF P14174 1/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51791 0.96 TYR (0.52) TYRGAAALDH1A1KMT2ATDP1
SCHEMBL10896936 0.89 TYR (0.47) TYRGAAALDH1A1KMT2ATDP1
SCHEMBL19842186 0.81 ALOX5 (0.48) TYRGAAALDH1A1KMT2ATDP1
SCHEMBL28295105 0.80 MEN1 (0.54) GAAALDH1A1KMT2ATDP1LMNA
SCHEMBL28478132 0.80 ALDH1A1 (0.41) TYRGAAALDH1A1KMT2ATDP1
SCHEMBL28295108 0.80 HPGD (0.51) GAAALDH1A1KMT2ATDP1POLB
SCHEMBL11758370 0.80 TYR (0.49) TYRGAAALDH1A1KMT2ATDP1
SCHEMBL28499022 0.80 CHRM1 (0.55) TYRGAAALDH1A1KMT2ATDP1
SCHEMBL1681823 0.80 TYR (0.73) TYRGAAALDH1A1KMT2AALOX5
SCHEMBL84243 0.79 TYR (0.67) TYRGAAALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4447593-A HIGH STRENGTH; MELT-SHAPEABLE; TEIJIN LIMITED (JP) 1984-05-08 US claimed
CN-100469826-C Phenols with antibacterial activity and compositions of inorganic material CIBA SC HOLDING AG (CH) 2009-03-18 CN disclosed
CN-1344758-A Phenols with antibacterial activity and compositions of inorganic material CIBA SC HOLDING AG (CH) 2002-04-17 CN disclosed
EP-0289802-B1 Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid DU PONT (US) 1997-10-15 EP disclosed
EP-0289802-A2 Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-09 EP disclosed
US-4746566-A Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid E. I. DUPONT DE NEMOURS AND COMPANY (US) 1988-05-24 US disclosed
EP-0072540-B1 MELT-ANISOTROPIC WHOLLY AROMATIC POLYESTER, PROCESS FOR PRODUCTION THEREOF, AND FIBERS OR FILMS THEREOF TEIJIN LIMITED (JP) 1986-04-23 EP disclosed
US-4447593-A HIGH STRENGTH; MELT-SHAPEABLE; TEIJIN LIMITED (JP) 1984-05-08 US disclosed
EP-0072540-A2 Melt-anisotropic wholly aromatic polyester, process for production thereof, and fibers or films thereof TEIJIN LIMITED (JP) 1983-02-23 EP disclosed