Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | MIF | P14174 | 1/20 | 0.65 |
| ▸ | TYR | P14679 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E319 SCHEMBL10904762 | 0.87 | TYR (0.69) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| E319 SCHEMBL31517209 | 0.85 | ALDH1A1 (0.67) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| E319 SCHEMBL6674211 | 0.85 | ALDH1A1 (0.67) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| E319 SCHEMBL10691852 | 0.83 | ALDH1A1 (0.80) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| SCHEMBL8772445 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| E319 SCHEMBL9392306 | 0.80 | ALDH1A1 (0.91) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| E319 SCHEMBL29350903 | 0.80 | ALDH1A1 (1.00) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| E319 SCHEMBL26745 | 0.80 | ALDH1A1 (1.00) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| E319 SCHEMBL27469266 | 0.80 | ALDH1A1 (1.00) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 | |
| SCHEMBL384263 | 0.79 | RARB (0.71) | ALDH1A1LMNAHSD17B10NR1I2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1767218-B1 | ANTIINFLAMMATORY AND ANALGESIC PREPARATION FOR EXTERNAL USE | HISAMITSU PHARMACEUTICAL CO (JP) | 2016-08-10 | — | — | EP | disclosed |
| US-8877813-B2 | Antiinflammatory and analgesic preparation for external use | HISAMITSU PHARMACEUTICALS CO., INC. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-20080031835-A1 | Antiinflammatory And Analgesic Preparation For External Use | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2008-02-07 | — | — | US | disclosed |
| EP-1767218-A1 | ANTIINFLAMMATORY AND ANALGESIC PREPARATION FOR EXTERNAL USE | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20050181031-A1 | Solifenacin transdermal preparation and method for enhancing transdermal permeation thereof | ASTELLAS PHARMA INC. (JP) | 2005-08-18 | — | — | US | disclosed |