SCHEMBL8772492

SCHEMBL8772492

NN1C=CSC1C(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
ALOX15 P16050 2/20 0.37
HTT P42858 1/20 0.37
HBB P68871 1/20 0.37
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
TSHR P16473 2/20 0.36
POLB P06746 1/20 0.36
PARP1 P09874 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 3/20 0.36
EPHX1 P07099 2/20 0.36
ALDH1A1 P00352 2/20 0.35
CES1 P23141 2/20 0.35
MEN1 O00255 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4957989 0.67 ACHE (0.39) MAPTCYP3A4TDP1TSHRPOLB
SCHEMBL11470621 0.63 MAPT (0.38) MAPTALOX15HTTHBBCYP3A4
SCHEMBL27459490 0.63 P2RX4 (0.40) MAPTTSHRCYP2C19L3MBTL1KMT2A
SCHEMBL669434 0.60 CES1 (0.58) MAPTALOX15CYP3A4TDP1TSHR
Benzoic Acid SCHEMBL28247425 0.58 TSHR (0.82) MAPTCYP3A4TDP1TSHRPOLB
SCHEMBL18428493 0.58 HTR2A (0.56) KMT2AALDH1A1MEN1CPB1MGLL
SCHEMBL3257215 0.58 MAPT (0.48) MAPTALOX15HTTHBBCYP3A4
SCHEMBL7850492 0.58 KMO (0.48) MAPTALOX15HTTHBBCYP3A4
SCHEMBL22570568 0.58 MCL1 (0.52) MAPTALOX15HTTHBBCYP3A4
SCHEMBL324342 0.58 HTR2A (0.56) KMT2AALDH1A1MEN1CPB1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0526170-B1 Dyestuff for heat-sensitive transfer record and transfer sheet containing same MITSUI TOATSU CHEMICALS (JP) 1997-10-08 EP disclosed
US-5567470-A COMPRISING A BENZO-2,1-ISOTHIAZOLE-AZO-PHENYL-TERTAMINES DYE; SOLVENT SOLUBILITY, LIGHT RESISTANCE, STORAGE STABILITY MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-10-22 US disclosed
US-5358536-A Dyestuff for heat-sensitive transfer record and transfer sheet containing same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-25 US disclosed
EP-0526170-A2 Dyestuff for heat-sensitive transfer record and transfer sheet containing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-03 EP disclosed