Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 16/20 | 0.70 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772636 | 0.87 | MMP13 (0.90) | MMP13FDFT1MMP2 | |
| SCHEMBL8772583 | 0.80 | MMP13 (0.63) | MMP13FDFT1MMP2 | |
| SCHEMBL8772804 | 0.78 | FDFT1 (0.73) | MMP13FDFT1MMP2 | |
| SCHEMBL8968958 | 0.77 | MMP13 (0.59) | MMP13FDFT1MMP2 | |
| SCHEMBL9431924 | 0.73 | MMP13 (0.52) | MMP13FDFT1MMP2 | |
| SCHEMBL8969537 | 0.73 | MMP13 (0.51) | MMP13FDFT1MMP2 | |
| SCHEMBL10411917 | 0.73 | ACACB (0.57) | — | |
| SCHEMBL4319225 | 0.71 | ACACB (0.62) | — | |
| SCHEMBL8968757 | 0.71 | FDFT1 (0.62) | MMP13FDFT1MMP2 | |
| Hydrochloric Acid SCHEMBL8772652 | 0.71 | MMP13 (0.62) | MMP13FDFT1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654032-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | disclosed |
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003451-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |