SCHEMBL877280

SCHEMBL877280

CCCCC1COC2(CCCC2)O1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
GAA P10253 1/20 0.45
ALDH1A1 P00352 3/20 0.39
TMEM97 Q5BJF2 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
HTR1A P08908 5/20 0.37
ADRA1D P25100 4/20 0.37
ADRA1B P35368 4/20 0.37
ADRA1A P35348 3/20 0.36
BRD4 O60885 1/20 0.35
ABL1 P00519 1/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 1/20 0.35
RIN1 Q13671 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 1/20 0.35
EPHX1 P07099 1/20 0.33
CYP1A2 P05177 1/20 0.32
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11175752 0.98 PABPC1 (0.51) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL11177497 0.98 PABPC1 (0.51) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL12943470 0.96 PABPC1 (0.45) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL11165380 0.93 ALDH1A1 (0.50) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL11163682 0.93 ALDH1A1 (0.50) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL11158688 0.93 ALDH1A1 (0.50) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL11163095 0.91 PABPC1 (0.49) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL11161053 0.91 PABPC1 (0.49) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL13381193 0.89 PABPC1 (0.51) PABPC1CTDSP1GAAALDH1A1TMEM97
SCHEMBL12943471 0.87 PABPC1 (0.54) PABPC1CTDSP1GAAALDH1A1TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028780-B1 2-ALKYL-1,4-DIOXASPIRO(4,N) ALKANES, THEIR PRODUCTION AND USE AS PERFUMES, AND PERFUME COMPOSITIONS CONTAINING THEM Henkel Kommanditgesellschaft auf Aktien (DE) 1983-07-27 EP claimed
EP-0028780-A1 2-Alkyl-1,4-dioxaspiro(4,n) alkanes, their production and use as perfumes, and perfume compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1981-05-20 EP claimed
CN-110891615-B System and method for selecting and releasing fragrance 阿甘香气及精细化学有限公司 2022-08-05 CN disclosed
CN-106999972-A System and method for discharging fragrance 阿甘芳香和精细化工有限公司 2017-08-01 CN disclosed
US-9358191-B2 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-06-07 US disclosed
EP-2757905-B1 ACETALS AND KETALS AS FRAGRANCES AND FLAVORS SYMRISE AG (DE) 2015-08-19 EP disclosed
US-8961946-B2 Hair processing agent and method for permanent waving hair SHOWA DENKO K.K. (JP) 2015-02-24 US disclosed
EP-2020225-B1 Fragrance composition KAO CORP (JP) 2014-10-08 EP disclosed
US-20140271522-A1 DEODORANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-09-18 US disclosed
US-8778320-B2 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-07-15 US disclosed
EP-1561476-B1 DEODORANT COMPOSITION TAKASAGO PERFUMERY CO LTD (JP) 2014-02-12 EP disclosed
US-20090087401-A1 DEODORANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-04-02 US disclosed
EP-2020225-A2 Fragrance composition Kao Corporation (JP) 2009-02-04 EP disclosed
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; RESONAC CORPORATION (JP) 2008-04-10 US disclosed
US-20060165622-A1 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-07-27 US disclosed
US-20050245407-A1 Fragrance composition KAO CORPORATION (JP) 2005-11-03 US disclosed
EP-1561476-A1 DEODORANT COMPOSITION Takasago International Corporation (JP) 2005-08-10 EP disclosed
EP-1552814-A1 FRAGRANCE COMPOSITION Kao Corporation (JP) 2005-07-13 EP disclosed
EP-0028780-B1 2-ALKYL-1,4-DIOXASPIRO(4,N) ALKANES, THEIR PRODUCTION AND USE AS PERFUMES, AND PERFUME COMPOSITIONS CONTAINING THEM Henkel Kommanditgesellschaft auf Aktien (DE) 1983-07-27 EP disclosed
EP-0028780-A1 2-Alkyl-1,4-dioxaspiro(4,n) alkanes, their production and use as perfumes, and perfume compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1981-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; TST, CYSLTR1, CYSLTR2 PABPC1 3813/4885CTDSP1 1497/4885GAA 2992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.