Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | BCHE | P06276 | 3/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772809 | 1.00 | FDPS (0.60) | FDPSACHEBCHEALOX5MAOB | |
| SCHEMBL16562710 | 0.95 | FDPS (0.63) | FDPSACHEBCHEALOX5MAOB | |
| SCHEMBL8772828 | 0.93 | FDPS (0.61) | FDPSACHEBCHEALOX5MAOB | |
| SCHEMBL8772825 | 0.93 | FDPS (0.61) | FDPSACHEBCHEALOX5MAOB | |
| SCHEMBL28386792 | 0.90 | HTR1A (0.60) | FDPSALOX5MEN1THRBKMT2A | |
| SCHEMBL10606238 | 0.87 | ABCB1 (0.67) | ALOX5HTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL10610360 | 0.87 | ABCB1 (0.67) | ALOX5HTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL28386689 | 0.86 | KDM4E (0.64) | ACHEMEN1THRBKMT2AHTR1A | |
| SCHEMBL8772845 | 0.84 | MAOB (0.68) | FDPSALOX5MAOBMEN1KMT2A | |
| SCHEMBL8772838 | 0.84 | MAOB (0.68) | FDPSALOX5MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801071-A1 | LEWIS X DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-15 | — | — | EP | disclosed |