Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 14/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431700 | 0.71 | ENPP2 (0.48) | ENPP2ESR1ESR2HSP90AA1ALDH1A1 | |
| SCHEMBL4532945 | 0.68 | ENPP2 (0.45) | ENPP2ESR1ESR2HSP90AA1ALDH1A1 | |
| SCHEMBL21596940 | 0.68 | ENPP2 (0.45) | ENPP2ESR1ESR2HSP90AA1ALDH1A1 | |
| SCHEMBL6818471 | 0.68 | ENPP2 (0.41) | ENPP2ESR1ESR2HSP90AA1ALDH1A1 | |
| SCHEMBL17437927 | 0.64 | CA12 (0.44) | ENPP2ESR2ALDH1A1MAPTKDM4E | |
| SCHEMBL13524013 | 0.62 | PIM1 (0.54) | ESR1ESR2ALDH1A1MAPTKDM4E | |
| SCHEMBL17941254 | 0.61 | TYR (0.39) | ESR1ESR2 | |
| SCHEMBL30513627 | 0.60 | TYR (0.58) | ALDH1A1MAPTALOX15HTTMEN1 | |
| SCHEMBL933119 | 0.60 | TYR (0.58) | ALDH1A1MAPTALOX15HTTMEN1 | |
| SCHEMBL4665771 | 0.60 | EGFR (0.46) | ALDH1A1MAPTKDM4EALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789692-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1997-08-20 | — | — | EP | disclosed |