Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 14/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431700 | 0.79 | ENPP2 (0.48) | ENPP2ESR1ESR2HSP90AA1ALDH1A1 | |
| SCHEMBL15922137 | 0.79 | KMT2A (0.41) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL4532945 | 0.76 | ENPP2 (0.45) | ENPP2ESR1ESR2HSP90AA1ALDH1A1 | |
| SCHEMBL2144895 | 0.76 | BACE1 (0.42) | ALDH1A1MAPTKDM4EHTTMEN1 | |
| SCHEMBL9214142 | 0.76 | NR4A2 (0.47) | ALDH1A1MAPTLMNAALOX15SMN1; SMN2 | |
| SCHEMBL21596938 | 0.72 | LMNA (0.37) | ALDH1A1LMNA | |
| SCHEMBL8947000 | 0.72 | ACHE (0.43) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL6818471 | 0.72 | ENPP2 (0.41) | ENPP2ESR1ESR2HSP90AA1ALDH1A1 | |
| SCHEMBL21596920 | 0.69 | PIK3CD (0.43) | HSP90AA1ALDH1A1MAPTKDM4EHTT | |
| SCHEMBL8772812 | 0.68 | ENPP2 (0.38) | ENPP2ESR1ESR2HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |