SCHEMBL8772867

SCHEMBL8772867

CCOC(CCBr)CCBr

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27348473 0.89
SCHEMBL8772875 0.89
SCHEMBL133831 0.84 OPRM1 (0.38) THRBLMNA
SCHEMBL1297783 0.77 THRB (0.40) THRBLMNA
SCHEMBL22654527 0.75 THRB (0.44) THRBLMNA
SCHEMBL21618241 0.75
SCHEMBL10764656 0.75 ALDH1A1 (0.47) LMNA
SCHEMBL21049755 0.74 THRB (0.38) THRBLMNA
SCHEMBL21049746 0.74 THRB (0.38) THRBLMNA
SCHEMBL27374323 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0625967-B1 N,N'-SUBSTITUTED IMIDOCARBONIMIDIC DIAMIDES DERIVED FROM HYDROXYLAMINES JACOBUS PHARMA CO INC (US) 1997-08-27 EP disclosed
US-5322858-A Antimicrobial, antiparasitic agents JACOBUS PHARMACEUTICAL CO. INC. (US) 1994-06-21 US disclosed