SCHEMBL8772876

SCHEMBL8772876

OC[C@H]1O[C@@H](c2cccc3ccccc23)[C@H](O)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PYGL P06737 1/20 0.55
SLC5A2 P31639 8/20 0.49
CD209 Q9NNX6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995764 1.00 PYGL (0.55) PYGLSLC5A2CD209
SCHEMBL8766883 0.88 EPHX1 (0.50) PYGLCD209
SCHEMBL25605620 0.86 PYGL (0.46) PYGLSLC5A2CD209
SCHEMBL3759096 0.86 PYGL (0.52) PYGLSLC5A2CD209
SCHEMBL23797741 0.83 LGALS3 (0.47) PYGLSLC5A2CD209
SCHEMBL23547663 0.83 LGALS3 (0.47) PYGLSLC5A2CD209
SCHEMBL2917657 0.78 SLC5A2 (0.57) PYGLSLC5A2
SCHEMBL27843034 0.78 EPHX1 (0.44) PYGLCD209
SCHEMBL440403 0.77 SLC5A2 (0.59) PYGLSLC5A2
SCHEMBL6542524 0.77 SLC5A2 (0.59) PYGLSLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0799313-A2 METHOD AND REAGENT FOR TREATMENT OF ARTHRITIC CONDITIONS, INDUCTION OF GRAFT TOLERANCE AND REVERSAL OF IMMUNE RESPONSES RIBOZYME PHARMACEUTICALS, INC. (US) 1997-10-08 EP disclosed
US-5672501-A Base-modified enzymatic nucleic acid RIBOZYME PHARMACEUTICALS, INC. (US) 1997-09-30 US disclosed
EP-0416817-B1 Amplification processes ZENECA LTD (GB) 1996-10-16 EP disclosed
US-5536537-A SILICONE EMULSIONS TOSHIBA SILICONE CO., LTD (JP) 1996-07-16 US disclosed
WO-1996018736-A2 METHOD AND REAGENT FOR TREATMENT OF ARTHRITIC CONDITIONS, INDUCTION OF GRAFT TOLERANCE AND REVERSAL OF IMMUNE RESPONSES RIBOZYME PHARMACEUTICALS, INC. (US) 1996-06-20 WO disclosed
US-5525494-A Amplification processes ZENECA LIMITED (GB) 1996-06-11 US disclosed
EP-0416817-A2 Amplification processes ZENECA LIMITED (GB) 1991-03-13 EP disclosed