Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006276 | 0.80 | ALDH1A1 (0.50) | GRM5 | |
| SCHEMBL28226588 | 0.80 | MAOB (0.41) | GRM5MAOAMAOB | |
| SCHEMBL28226645 | 0.80 | KDM4E (0.50) | GRM5MAOAMAOB | |
| SCHEMBL28316493 | 0.80 | GRM5 (0.38) | GRM5TSHRCOMTDRD4DRD2 | |
| SCHEMBL21603015 | 0.79 | APP (0.50) | GRM5COMTDRD4CYP3A4 | |
| SCHEMBL28226586 | 0.78 | GRM5 (0.48) | GRM5DRD2DRD3 | |
| SCHEMBL27858736 | 0.78 | GRM5 (0.48) | GRM5DRD2DRD3CYP3A4HTR1A | |
| SCHEMBL28226742 | 0.78 | GRM5 (0.48) | GRM5DRD2DRD3MAOAMAOB | |
| SCHEMBL1907012 | 0.78 | DDAH1 (0.47) | — | |
| SCHEMBL7825273 | 0.77 | GRM5 (0.47) | GRM5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492125-B1 | Insecticidal and synergistic miticidal compositions | AMERICAN CYANAMID CO (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5591765-A | ARYLPYRROLECARBONITRILE | AMERICAN CYANAMID COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0426948-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods | AMERICAN CYANAMID CO (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5455263-A | Administering substituted arylpyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1995-10-03 | — | — | US | disclosed |
| CN-1026206-C | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for preparation thereof | AMERICAN CYANAMID CO (US) | 1994-10-19 | — | — | CN | disclosed |
| EP-0347488-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5310938-A | Miticides, insecticides, parasiticides, and anthelmintics | AMERICAN CYANAMID COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5187184-A | Mixtures of substituted arylpyrroles and arylpyrazoles | AMERICAN CYANAMID COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0492125-A1 | Insecticidal and synergistic miticidal compositions | AMERICAN CYANAMID COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |
| CN-1058772-A | Desinsection, kill mite, nematocides aryl-pyrrolidine and preparation method thereof | AMERICAN CYANAMID CO (US) | 1992-02-19 | — | — | CN | disclosed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0358047-A2 | Method of controlling phytopathogenic fungi | AMERICAN CYANAMID COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| CN-1039807-A | Desinsection, kill mite, nematocides aryl-pyrrolidine and preparation method thereof | AMERICAN CYANAMID CO (US) | 1990-02-21 | — | — | CN | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| US-4857651-A | α-(2,3-Di(C1 -C4 alkoxy)ethylamino)-β-cyanostyrene and β-nitrostyrene compounds useful as intermediates in the preparation of insecticidal, acaricidal and nematicidal arylpyrroles and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |