Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.81 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | CA12 | O43570 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 2/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
| ▸ | CA9 | Q16790 | 2/20 | 0.66 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28729179 | 0.90 | EPHX2 (1.00) | EPHX2MAPTRAB9ACA12CA1 | |
| SCHEMBL11003408 | 0.90 | EPHX2 (1.00) | EPHX2MAPTRAB9ACA12CA1 | |
| SCHEMBL678654 | 0.86 | PTGS1 (1.00) | EPHX2PTGS1MAPTRAB9ACA12 | |
| SCHEMBL8772924 | 0.84 | RAB9A (1.00) | EPHX2PTGS1MAPTRAB9ACA12 | |
| SCHEMBL29572527 | 0.84 | KMT2A (0.77) | PTGS1MAPTRAB9ACA12CA1 | |
| SCHEMBL16246935 | 0.84 | KMT2A (0.77) | PTGS1MAPTRAB9ACA12CA1 | |
| SCHEMBL30969167 | 0.84 | PTGS1 (0.74) | EPHX2PTGS1MAPTRAB9ACA12 | |
| SCHEMBL7524681 | 0.83 | EPHX2 (0.78) | EPHX2PTGS1MAPTRAB9ACA12 | |
| SCHEMBL18031166 | 0.83 | EPHX2 (0.85) | EPHX2MAPTRAB9ACA12CA1 | |
| SCHEMBL4548071 | 0.83 | EPHX2 (0.85) | EPHX2MAPTRAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010144522-A1 | UREIDOPHENYL SUBSTITUTED TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | ABRAXIS BIOSCIENCE, LLC (US) | 2010-12-16 | — | — | WO | disclosed |