SCHEMBL8773023

SCHEMBL8773023

CCCOC(=O)N(CC)OCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.36
ALDH1A1 P00352 7/20 0.35
CHRM1 P11229 3/20 0.34
CHRNB2 P17787 3/20 0.34
CHRNA4 P43681 3/20 0.34
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM3 P20309 2/20 0.34
LMNA P02545 2/20 0.34
TSHR P16473 2/20 0.33
ESR1 P03372 1/20 0.33
SLC6A2 P23975 1/20 0.33
KDR P35968 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 1/20 0.32
KMT2A Q03164 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8773025 0.88 ALDH1A1 (0.48) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL8773032 0.84 ALDH1A1 (0.43) HCAR2ALDH1A1LMNATSHRHSD17B10
SCHEMBL6203840 0.78 ALDH1A1 (0.39) HCAR2ALDH1A1CHRM1CHRNB2CHRNA4
SCHEMBL8773026 0.77 ALDH1A1 (0.33) ALDH1A1LMNATSHRHSD17B10KMT2A
SCHEMBL8909513 0.75 MEN1 (0.45) HCAR2ALDH1A1CHRM1CHRNB2CHRNA4
SCHEMBL8773021 0.74 CHRNB2 (0.39) HCAR2ALDH1A1CHRM1CHRNB2CHRNA4
SCHEMBL27600863 0.74 KDM6B (0.34) ALDH1A1KMT2A
SCHEMBL10644883 0.74 NAAA (0.42) HCAR2ALDH1A1LMNATSHR
SCHEMBL18125074 0.73 CHRNB2 (0.46) HCAR2ALDH1A1CHRM1CHRNB2CHRNA4
SCHEMBL28644440 0.72 HDAC6 (0.40) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692469-B1 Process for recovering N,O-dialkylhydroxycarbamic acid ester MITSUI PETROCHEMICAL IND (JP) 1997-10-22 EP disclosed
EP-0581613-B1 Process for preparing N,O-dialkylhydroxycarbamic acid esters MITSUI PETROCHEMICAL IND (JP) 1996-09-11 EP disclosed
US-5510511-A REACTING HYDROXYLAMINE AND DIHYDROCARBYL CARBONATE WITH COOLING IN PRESENCE OF BASIC COMPOUND, ALKYLATING TO FORM N,O-DIALKYLHYDROXYCARBAMIC ACID ESTER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-04-23 US disclosed
EP-0692469-A1 Process for recovering N,O-dialkylhydroxycarbamic acid ester MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-01-17 EP disclosed
EP-0581613-A1 Process for preparing N,O-dialkylhydroxycarbamic acid esters MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-02-02 EP disclosed