Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL10561844 | 0.96 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1MAPTPABPC1 | |
| SCHEMBL10558089 | 0.83 | SHMT2 (0.56) | ALDH1A1KMT2AMEN1MAPTPABPC1 | |
| SCHEMBL10559807 | 0.83 | LTA4H (0.60) | ALDH1A1KMT2AMEN1MAPTPABPC1 | |
| SCHEMBL10560340 | 0.81 | SHMT2 (0.61) | ALDH1A1KMT2AMEN1MAPTSHMT2 | |
| SCHEMBL5203429 | 0.80 | SHMT2 (0.56) | ALDH1A1SHMT2KDM4EGAALMNA | |
| SCHEMBL10371775 | 0.78 | LTA4H (0.72) | ALDH1A1KMT2AMEN1MAPTPABPC1 | |
| SCHEMBL30894543 | 0.75 | MEN1 (0.55) | ALDH1A1KMT2AMEN1MAPTPABPC1 | |
| SCHEMBL28695467 | 0.75 | KDM4E (0.60) | ALDH1A1MAPTSHMT2KDM4EGAA | |
| SCHEMBL10557404 | 0.73 | ALDH1A1 (0.74) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL10557452 | 0.73 | POLB (0.66) | ALDH1A1KMT2AMEN1MAPTPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548233-B1 | PROCESSES FOR THE SYNTHESIS OF IMINES, ALDEHYDES, AND UNSYMMETRICAL SECONDARY AMINES | REILLY IND INC (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5424436-A | Processes for the synthesis of unsymmetrical secondary amines | REILLY INDUSTRIES, INC. (US) | 1995-06-13 | — | — | US | disclosed |
| US-5252741-A | Processes for the synthesis of imines, aldehydes, and unsymmetrical secondary amines | REILLY INDUSTRIES, INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0548233-A1 | PROCESSES FOR THE SYNTHESIS OF IMINES, ALDEHYDES, AND UNSYMMETRICAL SECONDARY AMINES. | REILLY IND INC (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992002507-A1 | PROCESSES FOR THE SYNTHESIS OF IMINES, ALDEHYDES, AND UNSYMMETRICAL SECONDARY AMINES | REILLY INDUSTRIES, INC. (US) | 1992-02-20 | — | — | WO | disclosed |
| US-4874775-A | INHIBIT PHYTOPATHOGENS | ELI LILLY AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| EP-0206581-A2 | Agriculturally-useful sulfonamides | ELI LILLY AND COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| CN-86103621-A | The method of the sulphonamide of preparation agriculturally useful | — | 1986-12-10 | — | — | CN | disclosed |