Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591450 | 0.80 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL9329488 | 0.79 | PTPRC (0.44) | MAOAMAOBHSD17B3BACE1NPC1 | |
| SCHEMBL26205055 | 0.74 | CDC25B (0.44) | MAOAGAPDHBACE1GSTP1NPC1 | |
| SCHEMBL29624480 | 0.71 | MAOA (0.41) | MAOAMAOBHSD17B3BACE1NPC1 | |
| SCHEMBL1895970 | 0.71 | MAOA (0.41) | MAOAMAOBHSD17B3BACE1NPC1 | |
| SCHEMBL16431948 | 0.69 | APAF1 (0.34) | GAPDHBACE1GSTP1 | |
| SCHEMBL2059539 | 0.68 | ALDH1A1 (0.38) | MAOAGAPDHGSTP1NPC1RAB9A | |
| SCHEMBL3132658 | 0.68 | MEN1 (0.34) | MAOAGAPDHGSTP1NPC1RAB9A | |
| SCHEMBL9473429 | 0.68 | CDC25A (0.42) | MAOAMAOBGAPDHGSTP1NPC1 | |
| SCHEMBL227263 | 0.68 | SLC2A1 (0.39) | MAOAGAPDHGSTP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439585-B1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS | MAG GEORG MAYRHOFER & CO OHG (AT) | 1997-10-29 | — | — | EP | disclosed |
| US-5196478-A | Polystyrene, assays | EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) | 1993-03-23 | — | — | US | disclosed |