Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771783 | 0.85 | FFAR1 (0.43) | CYP1A1CYP1A2CYP1B1FFAR1FFAR4 | |
| SCHEMBL8770919 | 0.82 | CYP1A1 (0.43) | CYP1A1CYP1A2CYP1B1FFAR1MAPT | |
| SCHEMBL8773470 | 0.79 | CYP1A1 (0.41) | CYP1A1CYP1A2CYP1B1FFAR1FFAR4 | |
| SCHEMBL8773383 | 0.78 | CYP1A1 (0.40) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL4242913 | 0.77 | MPO (0.43) | FFAR1FFAR4 | |
| SCHEMBL8770483 | 0.76 | GRM5 (0.47) | CYP1A1CYP1A2CYP1B1FFAR1FFAR4 | |
| SCHEMBL8773234 | 0.76 | CYP1A1 (0.41) | CYP1A1CYP1A2CYP1B1FFAR1FFAR4 | |
| SCHEMBL8772677 | 0.74 | CYP1A1 (0.40) | CYP1A1CYP1A2CYP1B1FFAR1FFAR4 | |
| SCHEMBL109397 | 0.73 | CA3 (0.48) | MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6 | |
| SCHEMBL7996636 | 0.72 | GRM5 (0.50) | CYP1A1CYP1A2CYP1B1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | CYP1A1 4/4885CYP1A2 18/4885CYP1B1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.