Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772677 | 0.85 | CYP1A1 (0.40) | CYP1A1CYP1A2CYP1B1PYGL | |
| SCHEMBL8770919 | 0.82 | CYP1A1 (0.43) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL19000283 | 0.80 | GABRP (0.37) | SLC6A4 | |
| SCHEMBL8773470 | 0.79 | CYP1A1 (0.41) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL8773288 | 0.78 | CYP1A1 (0.40) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL16235423 | 0.77 | VCAM1 (0.44) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL3817229 | 0.76 | PYGL (0.43) | CYP1A1CYP1A2CYP1B1PYGL | |
| SCHEMBL8773234 | 0.76 | CYP1A1 (0.41) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL15059793 | 0.75 | PYGL (0.40) | PYGLACACB | |
| SCHEMBL8771783 | 0.74 | FFAR1 (0.43) | CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | CYP1A1 4/4885CYP1A2 18/4885CYP1B1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.