Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773292 | 0.94 | ALDH1A1 (0.38) | ALDH1A1MAPTHSD17B10KDM4EGLA | |
| SCHEMBL21768314 | 0.93 | KMT2A (0.45) | ALDH1A1MAPTHPGDPRSS1TMPRSS15 | |
| SCHEMBL31216394 | 0.92 | KMT2A (0.44) | ALDH1A1HPGDPRSS1TMPRSS15KMT2A | |
| SCHEMBL19177135 | 0.80 | FOLH1 (0.47) | ALDH1A1MAPTKDM4EKMT2ACA2 | |
| SCHEMBL468918 | 0.80 | FOLH1 (0.47) | ALDH1A1MAPTKDM4EKMT2ACA2 | |
| SCHEMBL468916 | 0.80 | FOLH1 (0.47) | ALDH1A1MAPTKDM4EKMT2ACA2 | |
| SCHEMBL468757 | 0.78 | L3MBTL1 (0.54) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL468758 | 0.78 | L3MBTL1 (0.54) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL24978636 | 0.77 | TACR1 (0.56) | ALDH1A1HPGDKMT2ACA2CA1 | |
| SCHEMBL7046063 | 0.77 | TACR1 (0.56) | ALDH1A1HPGDKMT2ACA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627410-B1 | N-ACYLGLUTAMINE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1997-10-29 | — | — | EP | claimed |
| US-5468474-A | N-acylglutamine derivatives and cosmetic compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-11-21 | — | — | US | claimed |
| EP-0627410-A1 | N-ACYLGLUTAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-07 | — | — | EP | claimed |
| EP-0627410-B1 | N-ACYLGLUTAMINE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1997-10-29 | — | — | EP | disclosed |
| US-5468474-A | N-acylglutamine derivatives and cosmetic compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0627410-A1 | N-ACYLGLUTAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |