Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488668 | 0.87 | AOC3 (0.41) | AOC3SMN1; SMN2SLC6A2SLC6A4LMNA | |
| SCHEMBL10046522 | 0.82 | SIGMAR1 (0.43) | SIGMAR1KDM4EL3MBTL1POLBAPOBEC3A | |
| SCHEMBL9717165 | 0.81 | AOC3 (0.45) | SIGMAR1AOC3CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21731485 | 0.80 | AOC3 (0.44) | SIGMAR1AOC3MEN1KMT2AHTR2A | |
| SCHEMBL253120 | 0.76 | NPC1 (0.47) | AOC3SLC6A2SLC6A4TP53 | |
| SCHEMBL6491244 | 0.76 | AOC3 (0.47) | SIGMAR1AOC3SLC6A2SLC6A4KDM4E | |
| SCHEMBL6488829 | 0.74 | NPC1 (0.50) | SIGMAR1AOC3 | |
| SCHEMBL6477185 | 0.74 | NPC1 (0.50) | SIGMAR1AOC3 | |
| SCHEMBL6489577 | 0.74 | OPRM1 (0.39) | SIGMAR1AOC3MEN1KMT2AKDM4E | |
| SCHEMBL6484775 | 0.74 | NPC1 (0.50) | SIGMAR1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804142-A1 | DIKETO COMPOUNDS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022076-A1 | DIKETO COMPOUNDS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1996-07-25 | — | — | WO | disclosed |