SCHEMBL21731485 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	AOC3	Q16853	8/20	0.44

▸	HTR2A	P28223	2/20	0.40

▸	HRH1	P35367	2/20	0.40

▸	SIGMAR1	Q99720	2/20	0.35

▸	ALDH1A1	P00352	2/20	0.35

▸	MEN1	O00255	1/20	0.35

▸	HTT	P42858	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

▸	BCHE	P06276	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3685568	0.90	AOC3 (0.40)	AOC3HTR2AHRH1
SCHEMBL6491244	0.88	AOC3 (0.47)	AOC3HTR2AHRH1SIGMAR1ALDH1A1
SCHEMBL6490032	0.81	AOC3 (0.35)	AOC3HTR2AHRH1SIGMAR1
SCHEMBL9717165	0.81	AOC3 (0.45)	AOC3SIGMAR1ALDH1A1
SCHEMBL8773789	0.80	SIGMAR1 (0.39)	AOC3HTR2AHRH1SIGMAR1ALDH1A1
SCHEMBL87643	0.80	SIGMAR1 (0.46)	AOC3HTR2AHRH1SIGMAR1ALDH1A1
SCHEMBL4946334	0.79	AOC3 (0.50)	AOC3HTR2AHRH1SIGMAR1ALDH1A1
SCHEMBL13005300	0.78	HTR2A (0.46)	AOC3HTR2AHRH1SIGMAR1ALDH1A1
SCHEMBL449304	0.78	ESR1 (0.46)	AOC3MEN1HTTKMT2A
SCHEMBL6488668	0.77	AOC3 (0.41)	AOC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020035027-A1	LINKER, ANTIBODY-DRUG CONJUGATE INCLUDING SAME, AND USE THEREOF	中国人民解放军军事科学院军事医学研究院	2020-02-20	—	—	WO	disclosed