Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14266385 | 0.86 | KMT2A (0.53) | KMT2AALDH1A1MEN1ADORA3ADORA2A | |
| SCHEMBL9958891 | 0.82 | POLB (0.60) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL21681228 | 0.79 | TSHR (0.54) | KDM4EALDH1A1ADORA3ADORA2AADORA2B | |
| SCHEMBL2965336 | 0.78 | HNF4A (0.50) | KDM4EALDH1A1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL20303914 | 0.78 | ALB (0.55) | ALBKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29785235 | 0.78 | ALB (0.55) | ALBKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12637722 | 0.76 | ADORA3 (0.43) | KMT2AALDH1A1MEN1ADORA3ADORA2A | |
| SCHEMBL135374 | 0.76 | PLK1 (0.45) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL18230845 | 0.76 | POLB (0.51) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4607513 | 0.75 | ALB (0.49) | ALBKDM4EKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470669-B1 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5164502-A | Fluorinating agents | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5116982-A | Fluorination | DOWELANCO (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0470669-A2 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1992-02-12 | — | — | EP | disclosed |